PillRx only · Patch · Transdermal
Estradiol
Brands: Climara · Menostar · Estradiol
6 ACTIVE SUPPLIERS — US
openFDA · updated weekly
US49 NDCs
6 active makers
6 active makers
UKComing
soon
soon
CAComing
soon
soon
AUComing
soon
soon
EUComing
soon
soon
ATC—
RxCUI (US)—
US makers6 labelers
Packages49
DEA / ScheduleNone
US acquisition costNADAC · per unit
Average across 29 priced NDCs. A benchmark of pharmacy acquisition cost — not a retail quote.
$12.677
Latest avg · Jul 22, 2026
+1%
Since Dec 17, 2025
6
Active US suppliers
47%
Top-2 supplier share*
Medicaid dispensing volumeSDUD · per quarter
Prescriptions dispensed under Medicaid (fee-for-service + managed care), summed nationally. The closest free proxy to sales volume — Medicaid only, not all-payer.
207K
Rx · 2026 Q1
1.7M
Units dispensed
+65%
Rx vs. year ago
5
Quarters · since 2025 Q1
Who makes it6 active · 0 exited
US labelers as registered with FDA. Repackagers relabel another company's product; share* is of listed packages, not sales.
| Labeler | Type | Packages | Status |
|---|---|---|---|
| Mylan Pharmaceuticals Inc. | unknown | 16 | SUPPLYING |
| Bayer HealthCare LLC. | unknown | 7 | SUPPLYING |
| Zydus Lifesciences Limited | unknown | 7 | SUPPLYING |
| Zydus Pharmaceuticals USA Inc. | unknown | 7 | SUPPLYING |
| Sandoz Inc | unknown | 6 | SUPPLYING |
| A-S Medication Solutions | unknown | 6 | SUPPLYING |
Regulatory & supply eventsFDA · US
Shortages, recalls, and registration changes attached to this drug concept.
- Mar 15, 2021RECALLRecall (Class II): Estradiol Transdermal System, USP 0.1 mg/day (Twice-Weekly) Delivers 0.1 mg/day Rx only NDC 0378-4623-26 Manufactured f…
CGMP Deviations: Intermittent exposure to temperature excursion during storage. — Recalling firm: Cardinal Health Inc. — FL, GA, SC